Detalhe da pesquisa
1.
LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat Immunol
; 23(7): 1031-1041, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35761082
2.
The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
Immunity
; 54(6): 1154-1167.e7, 2021 06 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33979578
3.
Structural basis of GPBAR activation and bile acid recognition.
Nature
; 587(7834): 499-504, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698187
4.
Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling.
Nat Chem Biol
; 19(1): 9-17, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36050494
5.
Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.
Immunity
; 42(5): 815-25, 2015 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25992858
6.
Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer.
Nature
; 545(7654): 360-364, 2017 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28489825
7.
Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal.
Nature
; 545(7653): 238-242, 2017 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467820
8.
Inhibition of Delta-induced Notch signaling using fucose analogs.
Nat Chem Biol
; 14(1): 65-71, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29176671
9.
A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I.
J Virol
; 90(23): 10499-10512, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27630236
10.
Structure of the St. Louis encephalitis virus postfusion envelope trimer.
J Virol
; 87(2): 818-28, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23115296
11.
Soluble and multivalent Jag1 DNA origami nanopatterns activate Notch without pulling force.
Nat Commun
; 15(1): 465, 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38238313
12.
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells.
Dev Cell
; 59(9): 1110-1131.e22, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569552
13.
Crystal structure of the Japanese encephalitis virus envelope protein.
J Virol
; 86(4): 2337-46, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22156523
14.
New tricks for an old pathway: emerging Notch-based biotechnologies and therapeutics.
Trends Pharmacol Sci
; 44(12): 934-948, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37891017
15.
Structure of the planar cell polarity cadherins Fat4 and Dachsous1.
Nat Commun
; 14(1): 891, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36797229
16.
Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy.
Nat Cancer
; 4(2): 222-239, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36690875
17.
Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step.
J Virol
; 85(14): 7005-19, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21543495
18.
Functional Comparison between Endogenous and Synthetic Notch Systems.
ACS Synth Biol
; 11(10): 3343-3353, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36107643
19.
Discovery of an Orally Bioavailable Small-Molecule Inhibitor for the ß-Catenin/B-Cell Lymphoma 9 Protein-Protein Interaction.
J Med Chem
; 64(16): 12109-12131, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34382808
20.
Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling.
PLoS One
; 15(1): e0226928, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31914456